نوع مقاله : مقاله مروری

نویسندگان

1 دانشجوی دکتری علوم تشریحی،گروه علوم تشریحی، دانشکده پزشکی، دانشگاه علوم پزشکی شیراز، شیراز، ایران

2 دانشجوی دکتری عمومی دامپزشکی، دانشکده دامپزشکی، دانشگاه آزاد اسلامی واحد کازرون،کازرون، ایران

3 دانشیار گروه علوم تشریحی، دانشکده پزشکی، دانشگاه علوم پزشکی شیراز، شیراز، ایران

10.30476/smsj.2021.84394.1086

چکیده

امروزه ناباروری یکی از مشکلات شایع برای زوجین محسوب میشود و نیمی از علل آن مربوط به مردان است .حفظ پارامتر های اسپرم و کروماتین آن  در آزمایشگاه برای باروری موفقیت آمیزاین زوج ها ازاهمیت خاصی برخوردار است. عوامل متعددی از جمله دما، مدت زمان و روش های مختلف نگهداری اسپرم بر روی پارامتر های اسپرم و کروماتین آن موثر هستند. روش های مختلف نگهداری اسپرم هر یک دارای مزایا و معایبی هستند،از میان این روش ها انجماد شایع ترین روش است که قابلیت بارورسازی اسپرم را در یک دورة زمانی طولانی‌تر حفظ می‌کند. اگرچه باروری اسپرم ها در این روش، در مقایسه با مایع جنسی تازه کمتر است اما مزایای این روش از معایب آن بیشتر بوده و هنوز به عنوان ابزار مهمی برای نگهداری اسپرم در کلینیک های ناباروری مطرح است. ما با استفاده از پایگاه داده PubMed به انجام جستجو پرداختیم. درمطالعه ما، ترکیبی از اصطلاحات مرتبط با دما و مدت زمان نگهداری و هم چنین روش های مختلف نگهداری اسپرم و پارامتر های باروری وجود دارد.جستجو با استفاده ازAdvanced Search Builder انجام شد وکلمات کلیدی در "عنوان یا چکیده" یافت شدند.  این مطالعه، مروری براثرات دما ، مدت زمان و روش های مختلف نگهداری بر پارامتر های اسپرم و کرماتین آن می باشد تا بتوانیم شرایط و روش های بهینه برای نگهداری اسپرم را دریابیم.

کلیدواژه‌ها

عنوان مقاله [English]

A Review of the Effects of Temperature, Storage Duration, and Different Storage Methods on Sperm Parameters and Its Chromatin

نویسندگان [English]

  • Zohre Nateghian 1
  • Arvin Aliabadi 2
  • Elham Aliabadi 3

1 Ph.D. student, Department of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

2 DVM student, School of Veterinary Medicine, Kazerun Branch of Islamic Azad University, Kazerun, Iran

3 Associate Professor, Department of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

چکیده [English]

Infertility is now a common problem for couples and half of it is due to male infertility, so maintaining sperm parameters and its chromatin are important for successful fertility. Various factors such as temperature, storage duration, and different methods of sperm storage, including cryopreservation, affect these sperm parameters and fertility. Different methods of sperm storage have advantages and disadvantages; among which cryopreservation is the most common method of long-term storage of sperm; maintaining fertility over a longer period. However, sperm fertility in this method is lower than fresh sex fluid. Despite the problems of freezing, cryopreservation advantages outweigh its disadvantages and it is an important tool for sperm storage in clinics of infertility. We searched the PubMed database. In our study, there is a combination of terms related to temperature and storage time as well as different methods of sperm storage and fertility parameters. The search was performed using Advanced Search Builder and the keywords were found in "Title or Abstract". In this study, we reviewed the effects of temperature, storage duration, and different storage methods on sperm parameters and its chromatin to determine the optimal conditions and methods for sperm storage.

کلیدواژه‌ها [English]

  • Sperm storage
  • Storage temperature
  • Long term storage
  • Cryopreservation
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