نوع مقاله : مقاله مروری
نویسندگان
1 دکترای آموزش پرستاری، استادیار و عضو هیئت علمی دانشگاه علوم پزشکی قزوین، قزوین، ایران
2 دانشجوی کارشناسی ارشد روان پرستاری دانشگاه علوم پزشکی قزوین، قزوین، ایران
چکیده
اختلالات روانپزشکی شیوع بالایی در بین مراجعان به مراکز مراقبتهای اولیه و پزشکان عمومی دارند. هسته اصلی درمان در بیماران روانپزشکی دارو میباشد، این داروها در طولانیمدت میتواند عوارضی همچون کاهش یا فزایش قند و چربی را در پی داشته باشد. در این مطالعه به بررسی اثرات این داروها بر قند و چربی خون در ایران پرداخته شده است، لازم به ذکر میباشد که سطح قند خون و لیپید میتواند متأثر از جغرافیا، نژاد، قومیت و رنگ پوست باشد، کمااینکه مطالعات زیادی در این رابطه موجود میباشد و این روابط بیانشده به کرات به اثبات رسیده است. در این مطالعه مروری با استفاده از پایگاههای اطلاعاتی Mag Iran ،SID ، Iran Doc و Noormags تا پایان سال 1397 و پایگاههای اطلاعاتی بین الملیPubMed, ISI ,Web of knowledge Up To Date,و Google Scholar تا پایان سال 2019 جستجو انجام گردید و در نهایت تعداد 8 مطالعه از بین30 مطالعه، مورد بررسی نهایی قرار گرفتند. نتایج نشان داد کل افراد مورد بررسی در این مطالعه 824 نفر در 8 مقاله مورد بررسی بود. 6 مطالعه کارآزمایی بالینی، 1 مطالعه توصیفی و 1 مطالعه مورد- شاهدی میباشد. بهطور کلی در بررسی مطالعات حاضر، اکثر مطالعات تأثیر افزایشی آنتیسایکوتیکهای مهارکننده توأم را بر قند خون که از این دسته دارویی کلوزاپین و سپس ریسپریدون تاثیر بیشتری برایجاد این عارضه دارویی دارند و همچنین تاثیر داروهای آنتی سایکوتیک مهار کننده دوپامین بر چربی خون مشهود میباشد. در مقایسه کلومیپرامین و فلوکستین، کلومیپرامین موجب افزایش قند خون و چربی خون گردید، ولی فلوکستین این عوارض را نداشت.
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