مجله علوم پزشکی صدرا

بینش‌های مکانیسمی در مورد اثربخشی فیزیوتراپی برای نوروپاتی محیطی: یک مرور روایی

نوع مقاله : مقاله مروری

نویسندگان

مرضیه محمدی 1
فرحناز امامی 1
محمد مهدی زرنگار 2
ندا توکلی 2
مهشاد نصیری 2
حمیرا پریزاد 2

1 گروه فیزیوتراپی، دانشکده علوم توانبخشی، دانشگاه علوم پزشکی شیراز، شیراز، ایران

2 کمیته تحقیقات دانشجویی، دانشکده علوم توانبخشی، دانشگاه علوم پزشکی شیراز، شیراز، ایران

https://doi.org/10.30476/smsj.2026.107738.1661
چکیده
درمان نوروپاتی محیطی چالش‌برانگیز است؛ درک مکانیسم زیربنایی ممکن است منجر به انتخاب مؤثرترین درمان‌ها شود. این مقاله مکانیسم‌های زیربنایی رویکردهای فیزیکی برای درمان انواع مختلف نوروپاتی محیطی را بررسی می‌کند. پایگاه‌های داده PubMed، ScienceDirect و Google Scholar جستجو شدند. پس از غربالگری 161 مقاله و حذف موارد نامرتبط، 36 مطالعه شامل کارآزمایی‌های بالینی تصادفی و غیر تصادفی و همچنین بررسی‌های سیستماتیک انتخاب شدند. برای تسهیل تجزیه و تحلیل، مطالعات بر اساس شرایط زمینه‌ای به سه گروه طبقه‌بندی شدند: (1) نوروپاتی محیطی ناشی از شیمی‌درمانی، (2) نوروپاتی محیطی دیابتی و (3) سایر انواع نوروپاتی محیطی. در گروه اول، مداخلات مختلف فیزیوتراپی و روش‌های مختلف ورزشی بررسی شد، در گروه دوم اثرات روش‌های مختلف ورزشی ارزیابی شد، و در گروه سوم ورزش‌های هوازی و مقاومتی پیش‌رونده و همچنین درمان با ایجاد توهم لمس بررسی شد. این طبقه‌بندی امکان ارزیابی مداخلات توان‌بخشی مختلف مورد مطالعه در هر زیرگروه از نوروپاتی محیطی را ایجاد کرد. این مطالعه مروری نشان داد که مکانیسم‌هایی مانند محافظت عصبی، بازسازی عصب، اثرات ضد التهاب، کنترل قند خون، بهبود عملکرد عروقی، تعدیل درد، فعال‌سازی عضلات و نوروپلاستیسیته در اثربخشی این مداخلات نقش حیاتی دارند.

تازه های تحقیق

Marzieh Mohamadi (Google Scholar)

Farahnaz Emami (Google Scholar)

کلیدواژه‌ها

بیماری‌های دستگاه عصبی محیطی
نوروپاتی‌های دیابتی
رشته‌های عصبی
مکانیسم‌های اثر
پیامدهای درمان
روش‌های فیزیوتراپی
ورزش
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مجله علوم پزشکی صدرا
دوره 14، شماره 2
تابستان 1405
صفحه 500-517

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