نوع مقاله: مقاله پژوهشی

نویسندگان

1 استادیار، مرکز تحقیقات ارتقاء سلامت، دانشگاه علوم پزشکی زاهدان، زاهدان، ایران

2 کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی زاهدان، زاهدان، ایران

3 استاد، مرکز تحقیقات ارتقاء سلامت، دانشگاه علوم پزشکی زاهدان، زاهدان، ایران

چکیده

مقدمه: مطالعات حاکی از این است که مهمترین عامل محدودکننده باروری و حاصل تولید مثلی سالم با وجود یک زوج مسن تر، سن زنان است. اما این سوال برانگیخته می شود که تا چه حد سن پدر بر دوره بارداری و بیش از همه بر سلامت نوزاد تاثیر می‌گذارد. لذا هدف از مطالعه حاضر تعیین رابطه بین سن پدر با پیامدهای باروری بود.مواد و روش: این پژوهش از نوع کوهورت گذشته‌نگر بود که با هدف کاربردی در شهر زاهدان در سال 1395 انجام گرفت. جامعه آماری شامل پرونده 3000 کودک زیر یک سال شهر زاهدان بود که از مراکز بهداشتی درمانی مختلف شهری انتخاب شدند. داده‌ها با استفاده از چک لیست استاندارد جمع‌آوری شدند. برای تحلیل داده ها از نرم افزار SPSS ، آمار توصیفی و آزمون کای-اسکوئر استفاده شد.یافته‌ها : اکثر پدران در محدوده سنی 20 تا 40 سال قرار داشتند. اکثریت خانواده‌های مورد مطالعه دارای یک فرزند بوده و اکثر کودکان مورد بررسی فرزند اول خانواده بودند. نتایج مطالعه، حاکی از ارتباط بین سن پدر و جنسیت نوزاد (017/0P = )، وزن هنگام تولد نوزاد (031/0P = )، نوع زایمان مادر (001/0P = ) و زمان زایمان (013/0P =) بود.بحث و نتیجه گیری: با افزایش سن پدر احتمال بروز عوامل خطر از جمله زایمان زودرس و انجام سزارین وجود داشت. فرزند‌آوری در سنین جوانی احتمال تولد نوزاد سالم را بیشتر می‌کند. پیشنهاد می‌شود جهت کاهش زایمان‌های زودرس و پرخطر و کاهش هزینه‌های خانوارها و نظام سلامت فرزندآوری خانواده‌ها بیشتر در سنین جوانی والدین انجام گردد.

کلیدواژه‌ها

عنوان مقاله [English]

The Relationship between Fathers’ Age and the Consequences of Fertility: A Cross Sectional Study at Zahedan University of Medical Sciences

نویسندگان [English]

  • Mohammad Khammarnia 1
  • Soudabeh Moradi 2
  • Shaghayegh Abasi 2
  • Alireza Ansari-Moghadam 3
  • Fatemeh Setoodehzadeh 1

1 Assistant Professor, Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran

2 Student research committee, Zahedan University of Medical Sciences, Zahedan, Iran

3 Full Professor, Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran

چکیده [English]

Background: Studies show that the most important limiting factor for fertility and a healthy reproduction with an older couple is women’s age. But the question is that to what extent will the father's age affect pregnancy and infant health? The aim of this study was to determine the relationship between paternal ages with reproductive outcomes.
Methods: This retrospective cohort study was conducted in Zahedan in 2017. The study population included 3,000 children under one year of age who were selected from urban health centers of Zahedan. Data were collected using a standard checklist. SPSS software, descriptive statistics, chi-square test, and logistic regression were used for data analysis.
Results: Most fathers were 20 to 40 years old. The majority of the studied families had one child and most children examined were the first child. The results showed an association between paternal age and the sex of the baby (P=0.017), birth weight (P 0.031P =), type of delivery (P= 0.001) and delivery time (P=0.013).
Conclusion: With increasing paternal age, there is the possibility of developing risk factors such as early delivery and cesarean section. Childbearing at a young age increases the likelihood of having a healthy baby.  In order to reduce early and high risk pregnancies and household costs, and health systems, it is suggested that the childbearing of family take place when parents are younger.

کلیدواژه‌ها [English]

  • Parent
  • Reproduction
  • Fathers
  • Community Health Center

1. Tatone C. Oocyte senescence: a firm link to age-related female subfertility. Gynecological Endocrinolology 2008; 24:59–63.

2. Balasch J. Ageing and infertility: an overview. Gynecological Endocrinology 2010; 26:855–60.

3. Sartorius GA, Nieschlag E. Paternal age and reproduction. Human Reproduction Update 2010; 16:65–79.

4. Amann RP. The cycle of the seminiferous epithelium in humans: a need to revisit? Journal of Androlology 2008; 29:469–87.

5. Ford WC, North K, Taylor H, Farrow A, Hull MG, Golding J. Increasing paternal age is associated with delayed conception in a large population of fertile couples: evidence for declining fecundity in older men. The ALSPAC Study Team (Avon Longitudinal Study of Pregnancy and Childhood). Human Reproduction 2000; 15:1703–8.

6. Sartorius GA, Nieschlag E. Paternal age and reproduction. Human Reproduction Update 2010; 16:65–79.

7. Dain L, Auslander R, Dirnfeld M. The effect of paternal age on assisted reproduction outcome. Fertility and Sterility 2011; 95:1-8.

8. Alio AP, Salihu HM, McIntosh C, August EM, Weldeselasse H, Sanchez E, et al. The effect of paternal age on fetal birth outcomes. American Journal of Mens Health 2012; 6:427–35.

9. Lee DM, Tajar A, Ravindrarajah R, Pye SR, OConnor DB, Corona G, et al., and European Male Aging Study Group. Frailty and sexual health in older European men. Journal of Gerontololgy 2013; 68:837–44.

10. Nicolosi A, Buvat J, Glasser DB, Hartmann U, Laumann EO, Gingell C, and GSSAB Investigators’ Group. Sexual behaviour, sexual dysfunctions and related help seeking patterns in middle-aged and elderly Europeans: the global study of sexual attitudes and behaviors. World Journal of Urology 2006; 24: 423–8.

11. Wiener-Megnazi Z, Auslender R, Dirnfeld M. Advanced paternal age and reproductive outcome. Asian Journal of Androlology 2012; 14:69–76.

12. Miller B, Messias E, Miettunen J, Alaräisänen A, Järvelin MR, Koponen H, et al. Meta-analysis of paternal age and schizophrenia risk in male versus female offspring. Schizophrenia Bulletins 2010; 37:1039–47.

13. Sipos A, Rasmussen F, Harrison G, Harrison G, Tynelius P, Lewis G, Leon DA, Gunnell D. Paternal age and schizophrenia: a population based cohort study. British Medical Journal 2004; 329:1070.

14. Frans EM, Sandin S, Reichenberg A, Lichtenstein P, Långström N, Hultman CM. Advancing paternal age and bipolar disorder. Archives of Genetic Psychiatry 2008; 65:1034–40.

15. Malaspina D, Reichenberg A, Weiser M, Fennig S, Davidson M, Harlap S. Paternal age and intelligence: implications for age-related genomic changes in male germ cells. Psychiatric Genetics 2005; 15(2):117–25.

16. Whitley E, Deary IJ, Batty GD, Benzeval M. Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. PLoS One 2012; 7: 52112.

17. Yip BH, Pawitan Y, Czene K. Parental age and risk of childhood cancers: a population based cohort study from Sweden. International Journal of Epidemiology 2006; 35:1495–503.

18. Montgomery SM, Lambe M, Olsson T, Ekbom A. Parental age, family size, and risk of multiple sclerosis. Epidemiology 2004; 15:717-23.

19. Lolai A, Kashani zadeh N. Epidemiological study of pregnancy outcome in 50 wives of chemical warfare injured in Kerman province. Military Medicine 2003; 5(4):269-276

20. Sasanfar R, Haddad SA, Tolouei A, Ghadami M, Yu D, Santangelo SL. Paternal age increases the risk for autism in an Iranian population sample. Mol Autism 2010; 22; 1(1):2

21. Malaspina D, Harlap S, Fennig S, Heiman D, Nahon D, Feldman D, Susser ES. Advancing paternal age and the risk of schizophrenia. Arch Gen Psychiatry. 2001; 58:361-367.