Sadra Medical Journal

Investigation of the diagnostic value of aphasia and sensory-motor sings for topographic detection of lesions in the patients with cerebrovascular syndrome

Document Type : Original Article

Authors

kavian ghandehari
atena Sharifi Razavi
amir Moghaddam Ahmadi
mahsa sepandar
mahmoud Taheri Heravi
saeed Ebrahimzadeh

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Abstract
Methods: In this study, 200 patients who had undergone brain MRI and had a single new well defined cerebrovascular lesion in the brain underwent neuroexamination and were categorized based on syndrome diagnosis. This clinical evaluation was performed by a neurologist who was blind to the result of brain MRI. Also, the topography of vascular and parenchymal lesions was reported by a neuroradiologist who was blind to the clinical data. Then, true, false positive and false negative cases were identified compared to the standard method for determination of lesions topography; i.e., brain MRI. Afterwards, sensitivity, specificity, positive and negative predictive values, and accuracy of these syndromes were assessed.
Results: The diagnostic accuracy of broca and wernicke aphasia for localization of brain lesion in lateral left frontal and left temporoparietal was 94%. Besides, the accuracy of hemiparesis for localization of brain lesion in the contralateral hemisphere was 95%. Additionally, the accuracy of aphasia and hemihypoesthesia for localization of brain lesion in the left hemisphere and contralateral hemisphere was 100%.
Conclusion: Topography of symptomatic cerebrovascular lesions could be more accurately determined using clinical neuroexamination skills for detection of neurological syndromes.

Keywords

Syndrome
Lesion
Topography
Brain
Sadra Medical Journal
Volume 2, Issue 2
Spring 2014
Pages 143-150

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